Prime Video Sets Premiere Date and Shares First Look at Season 2 of The Second Best Hospital in the Galaxy
Get ready for more chaos in space! Prime Video has confirmed that all eight episodes of The Second Best Hospital in the Galaxy Season 2 will premiere on Tuesday, May 27, 2025. The new season will be available to stream worldwide in over 240 countries and territories.
The Second Best Hospital in the Galaxy Season 1 is streaming now on Prime Video. Here is the best time to rewatch and catchup with the season 1.
What to Expect in Season 2
This animated sci-fi comedy series follows two fearless surgeons, Dr. Sleech and Dr. Klak. They are not only top doctors but also best friends who face strange, life-threatening medical cases from all across the universe.
In Season 2, the duo is riding high after a recent success that made them famous. But the spotlight comes with problems. A robotic journalist begins to dig into Dr. Sleech’s hidden past, threatening to reveal secrets that could change everything.
The show combines action, comedy, and intergalactic drama, making it a must-watch for fans of adult animation.
Cast and Crew Behind the Series
The series features a talented lineup of voice actors, including:
- Stephanie Hsu (Everything Everywhere All at Once)
- Keke Palmer (One of Them Days)
- Kieran Culkin (A Real Pain)
- Sam Smith (Spectre)
- Maya Rudolph (Loot)
- Natasha Lyonne (Poker Face)
Season 2 also welcomes:
- Tracee Ellis Ross (American Fiction, Black-ish)
- Abbi Jacobson (Broad City)
- Andrew Dismukes (Saturday Night Live)
- Bowen Yang (Saturday Night Live, Fire Island)
- Gary Anthony Williams (Night Court)
- Lennon Parham (Minx)
- Jay Ellis (Top Gun: Maverick)
- Kemah Bob (Springleaf)
- John Waters (Hairspray)
Cirocco Dunlap returns as the creator, showrunner, writer, and executive producer. She is joined by executive producers Maya Rudolph, Natasha Lyonne, and Danielle Renfrew Behrens from Animal Pictures. Additional executive producers include Shauna McGarry, Shannon Prynoski, Chris Prynoski, Antonio Canobbio, and Ben Kalina from Titmouse.
The show’s colorful space visuals are crafted by Robin Eisenberg, who also serves as co-producer and production designer.
Catch every episode of The Second Best Hospital in the Galaxy Season 2, streaming only on Prime Video starting May 27, 2025.